Deferasirox improves liver fibrosis in beta‐thalassaemia major patients. A five‐year longitudinal study from a single thalassaemia centre

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Longitudinal Study on Liver Functions in Patients with Thalassemia Major before and after Deferasirox (DFX) Therapy

UNLABELLED By performing regular blood transfusion and iron chelation therapy, most patients with beta thalassemia major (BTM) now survive beyond the third decade of life. Liver disease is becoming an important cause of morbidity and mortality in these patients. Chronic hepatitis and/or severe iron overload are both important causes of liver pathology. Iron chelation with desferrioxamine (DFO) ...

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Prevalence of hepatitis C infection among children with β-thalassaemia major in Mid Delta, Egypt: a single centre study.

BACKGROUND Transfusion dependant patients are at a higher risk of acquiring bloodborne infections even under conditions of safe transfusion. This study was designed to determine sero-prevalence of hepatitis C infection and possible associated risk factors in thalassaemic children. METHODS One hundred and twenty five children with β thalassaemia major (β-TM) were recruited from the Haematology...

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2017

ISSN: 0007-1048,1365-2141

DOI: 10.1111/bjh.14509